When Ground Isn't Fast Enough
When your shipment needs to take flight, we’re ready for takeoff.
Whether via commercial airline or charter, we evaluate every variable—weather, connecting routes, traffic, time zones, and airport logistics—to secure the most optimal flight path for your delivery.
Many of our drivers are also on-board couriers (OBCs), offering the highest level of chain of custody and shipment security. As TSA-certified personnel, they can navigate secure areas and ensure your shipment stays in trusted hands from pickup to flight to final delivery—no handoffs, no gaps in visibility.
Lean on us for:
- Direct-to-Tarmac Courier Access
- TSA-Certified On-Board Couriers
- Secure Chain of Custody
- End-to-end coordination from pickup to final delivery
Why Choose Next Flight Out?
Because sometimes, same-day just isn’t fast enough.
When a shipment is too urgent—or too valuable—for standard ground or freight, next flight out is the fastest path forward. Whether you're moving transplant tissue, clinical trial specimens, or AOG parts, we deliver with the urgency the moment demands.
With direct airline access, TSA-certified couriers, and real-time coordination, we keep your shipment in trusted hands—every step of the way.

Confidence at Cruising Altitude
We manage the entire NFO process—from booking the best flight to securing last-mile delivery—so nothing is left to chance. Every variable is accounted for: weather, delays, connections, TSA regulations, and airport logistics.
Whether it flies commercial or charter, we make sure it lands on time—and in the right hands.
End-to-End
Single Point of Contact
Real-time Updates from Pickup to Delivery
Risk-Managed Contingency Plans
Built-in Compliance & Documentation
CASE STUDY
Recovering a Failed Organ Delivery in Time to Save a Life
When another courier couldn’t fulfill a high-stakes organ transplant delivery, American Expediting was called in to rescue the mission. With less than 8 hours left in the organ’s cold-time viability window, we coordinated drivers, secured a private charter, arranged a police escort, and delivered the kidney in time for a successful transplant—before the expiration window closed.

A Reputation Built in the Toughest Moments
“When lives are on the line, we need a courier that can deliver—literally and figuratively. American Expediting’s Next Flight Out service has been critical to our kidney transplant program, consistently executing urgent shipments with less than 8 hours' notice. In 2024 alone, they supported 95% of our transplant shipments nationwide, helping us uphold the highest standards of care.”
Logistics Director, National Transplant Organization
“Working in animal research, there’s no wiggle room for delays—especially when you're shipping time-sensitive materials. American Expediting has been a steady hand for us. Their NFO team doesn’t just move fast—they communicate, follow through, and make the whole process feel easy, even when it’s not. They’ve earned our trust, one urgent delivery at a time.”
Animal Biotech Industries, Operations Team
“We trusted American Expediting with the first-ever dose delivery for a groundbreaking clinical trial—and they delivered flawlessly. From coordinating with the airport to navigating customs and ensuring real-time updates every step of the way, their team executed with urgency, care, and precision. Their expertise in high-stakes, temperature-sensitive shipments gave us the confidence we needed to move forward, knowing lives were on the line.”
Clinical Operations Lead, Global Rare Disease Trial Sponsor
“When we had an AOG situation, American Expediting moved fast—coordinating a next flight out shipment that got the part where it needed to be, without delay. Their team understood the urgency, handled the handoff with care and efficiency, and kept us updated every step of the way. Knowing their drivers are TSA-certified gave us added confidence that everything would move securely and without disruption. That kind of responsiveness is exactly what we need when every minute counts.”
Maintenance Supervisor, Global Aviation Company